Source code for monai.data.image_reader

# Copyright (c) MONAI Consortium
# Licensed under the Apache License, Version 2.0 (the "License");
# you may not use this file except in compliance with the License.
# You may obtain a copy of the License at
#     http://www.apache.org/licenses/LICENSE-2.0
# Unless required by applicable law or agreed to in writing, software
# distributed under the License is distributed on an "AS IS" BASIS,
# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
# See the License for the specific language governing permissions and
# limitations under the License.

from __future__ import annotations

import glob
import os
import warnings
from abc import ABC, abstractmethod
from collections.abc import Callable, Iterable, Iterator, Sequence
from dataclasses import dataclass
from pathlib import Path
from typing import TYPE_CHECKING, Any

import numpy as np
from torch.utils.data._utils.collate import np_str_obj_array_pattern

from monai.config import KeysCollection, PathLike
from monai.data.utils import (
    affine_to_spacing,
    correct_nifti_header_if_necessary,
    is_no_channel,
    is_supported_format,
    orientation_ras_lps,
)
from monai.utils import MetaKeys, SpaceKeys, TraceKeys, ensure_tuple, optional_import, require_pkg

if TYPE_CHECKING:
    import itk
    import nibabel as nib
    import nrrd
    import pydicom
    from nibabel.nifti1 import Nifti1Image
    from PIL import Image as PILImage

    has_nrrd = has_itk = has_nib = has_pil = has_pydicom = True
else:
    itk, has_itk = optional_import("itk", allow_namespace_pkg=True)
    nib, has_nib = optional_import("nibabel")
    Nifti1Image, _ = optional_import("nibabel.nifti1", name="Nifti1Image")
    PILImage, has_pil = optional_import("PIL.Image")
    pydicom, has_pydicom = optional_import("pydicom")
    nrrd, has_nrrd = optional_import("nrrd", allow_namespace_pkg=True)

__all__ = ["ImageReader", "ITKReader", "NibabelReader", "NumpyReader", "PILReader", "PydicomReader", "NrrdReader"]


[docs] class ImageReader(ABC): """ An abstract class defines APIs to load image files. Typical usage of an implementation of this class is: .. code-block:: python image_reader = MyImageReader() img_obj = image_reader.read(path_to_image) img_data, meta_data = image_reader.get_data(img_obj) - The `read` call converts image filenames into image objects, - The `get_data` call fetches the image data, as well as metadata. - A reader should implement `verify_suffix` with the logic of checking the input filename by the filename extensions. """
[docs] @abstractmethod def verify_suffix(self, filename: Sequence[PathLike] | PathLike) -> bool: """ Verify whether the specified `filename` is supported by the current reader. This method should return True if the reader is able to read the format suggested by the `filename`. Args: filename: file name or a list of file names to read. if a list of files, verify all the suffixes. """ raise NotImplementedError(f"Subclass {self.__class__.__name__} must implement this method.")
[docs] @abstractmethod def read(self, data: Sequence[PathLike] | PathLike, **kwargs) -> Sequence[Any] | Any: """ Read image data from specified file or files. Note that it returns a data object or a sequence of data objects. Args: data: file name or a list of file names to read. kwargs: additional args for actual `read` API of 3rd party libs. """ raise NotImplementedError(f"Subclass {self.__class__.__name__} must implement this method.")
[docs] @abstractmethod def get_data(self, img) -> tuple[np.ndarray, dict]: """ Extract data array and metadata from loaded image and return them. This function must return two objects, the first is a numpy array of image data, the second is a dictionary of metadata. Args: img: an image object loaded from an image file or a list of image objects. """ raise NotImplementedError(f"Subclass {self.__class__.__name__} must implement this method.")
def _copy_compatible_dict(from_dict: dict, to_dict: dict): if not isinstance(to_dict, dict): raise ValueError(f"to_dict must be a Dict, got {type(to_dict)}.") if not to_dict: for key in from_dict: datum = from_dict[key] if isinstance(datum, np.ndarray) and np_str_obj_array_pattern.search(datum.dtype.str) is not None: continue to_dict[key] = str(TraceKeys.NONE) if datum is None else datum # NoneType to string for default_collate else: affine_key, shape_key = MetaKeys.AFFINE, MetaKeys.SPATIAL_SHAPE if affine_key in from_dict and not np.allclose(from_dict[affine_key], to_dict[affine_key]): raise RuntimeError( "affine matrix of all images should be the same for channel-wise concatenation. " f"Got {from_dict[affine_key]} and {to_dict[affine_key]}." ) if shape_key in from_dict and not np.allclose(from_dict[shape_key], to_dict[shape_key]): raise RuntimeError( "spatial_shape of all images should be the same for channel-wise concatenation. " f"Got {from_dict[shape_key]} and {to_dict[shape_key]}." ) def _stack_images(image_list: list, meta_dict: dict): if len(image_list) <= 1: return image_list[0] if not is_no_channel(meta_dict.get(MetaKeys.ORIGINAL_CHANNEL_DIM, None)): channel_dim = int(meta_dict[MetaKeys.ORIGINAL_CHANNEL_DIM]) return np.concatenate(image_list, axis=channel_dim) # stack at a new first dim as the channel dim, if `'original_channel_dim'` is unspecified meta_dict[MetaKeys.ORIGINAL_CHANNEL_DIM] = 0 return np.stack(image_list, axis=0)
[docs] @require_pkg(pkg_name="itk") class ITKReader(ImageReader): """ Load medical images based on ITK library. All the supported image formats can be found at: https://github.com/InsightSoftwareConsortium/ITK/tree/master/Modules/IO The loaded data array will be in C order, for example, a 3D image NumPy array index order will be `CDWH`. Args: channel_dim: the channel dimension of the input image, default is None. This is used to set original_channel_dim in the metadata, EnsureChannelFirstD reads this field. If None, `original_channel_dim` will be either `no_channel` or `-1`. - Nifti file is usually "channel last", so there is no need to specify this argument. - PNG file usually has `GetNumberOfComponentsPerPixel()==3`, so there is no need to specify this argument. series_name: the name of the DICOM series if there are multiple ones. used when loading DICOM series. reverse_indexing: whether to use a reversed spatial indexing convention for the returned data array. If ``False``, the spatial indexing follows the numpy convention; otherwise, the spatial indexing convention is reversed to be compatible with ITK. Default is ``False``. This option does not affect the metadata. series_meta: whether to load the metadata of the DICOM series (using the metadata from the first slice). This flag is checked only when loading DICOM series. Default is ``False``. affine_lps_to_ras: whether to convert the affine matrix from "LPS" to "RAS". Defaults to ``True``. Set to ``True`` to be consistent with ``NibabelReader``, otherwise the affine matrix remains in the ITK convention. kwargs: additional args for `itk.imread` API. more details about available args: https://github.com/InsightSoftwareConsortium/ITK/blob/master/Wrapping/Generators/Python/itk/support/extras.py """ def __init__( self, channel_dim: str | int | None = None, series_name: str = "", reverse_indexing: bool = False, series_meta: bool = False, affine_lps_to_ras: bool = True, **kwargs, ): super().__init__() self.kwargs = kwargs self.channel_dim = float("nan") if channel_dim == "no_channel" else channel_dim self.series_name = series_name self.reverse_indexing = reverse_indexing self.series_meta = series_meta self.affine_lps_to_ras = affine_lps_to_ras
[docs] def verify_suffix(self, filename: Sequence[PathLike] | PathLike) -> bool: """ Verify whether the specified file or files format is supported by ITK reader. Args: filename: file name or a list of file names to read. if a list of files, verify all the suffixes. """ return has_itk
[docs] def read(self, data: Sequence[PathLike] | PathLike, **kwargs): """ Read image data from specified file or files, it can read a list of images and stack them together as multi-channel data in `get_data()`. If passing directory path instead of file path, will treat it as DICOM images series and read. Note that the returned object is ITK image object or list of ITK image objects. Args: data: file name or a list of file names to read, kwargs: additional args for `itk.imread` API, will override `self.kwargs` for existing keys. More details about available args: https://github.com/InsightSoftwareConsortium/ITK/blob/master/Wrapping/Generators/Python/itk/support/extras.py """ img_ = [] filenames: Sequence[PathLike] = ensure_tuple(data) kwargs_ = self.kwargs.copy() kwargs_.update(kwargs) for name in filenames: name = f"{name}" if Path(name).is_dir(): # read DICOM series # https://examples.itk.org/src/io/gdcm/readdicomseriesandwrite3dimage/documentation names_generator = itk.GDCMSeriesFileNames.New() names_generator.SetUseSeriesDetails(True) names_generator.AddSeriesRestriction("0008|0021") # Series Date names_generator.SetDirectory(name) series_uid = names_generator.GetSeriesUIDs() if len(series_uid) < 1: raise FileNotFoundError(f"no DICOMs in: {name}.") if len(series_uid) > 1: warnings.warn(f"the directory: {name} contains more than one DICOM series.") series_identifier = series_uid[0] if not self.series_name else self.series_name name = names_generator.GetFileNames(series_identifier) name = name[0] if len(name) == 1 else name # type: ignore _obj = itk.imread(name, **kwargs_) if self.series_meta: _reader = itk.ImageSeriesReader.New(FileNames=name) _reader.Update() _meta = _reader.GetMetaDataDictionaryArray() if len(_meta) > 0: # TODO: using the first slice's meta. this could be improved to filter unnecessary tags. _obj.SetMetaDataDictionary(_meta[0]) img_.append(_obj) else: img_.append(itk.imread(name, **kwargs_)) return img_ if len(filenames) > 1 else img_[0]
[docs] def get_data(self, img) -> tuple[np.ndarray, dict]: """ Extract data array and metadata from loaded image and return them. This function returns two objects, first is numpy array of image data, second is dict of metadata. It constructs `affine`, `original_affine`, and `spatial_shape` and stores them in meta dict. When loading a list of files, they are stacked together at a new dimension as the first dimension, and the metadata of the first image is used to represent the output metadata. Args: img: an ITK image object loaded from an image file or a list of ITK image objects. """ img_array: list[np.ndarray] = [] compatible_meta: dict = {} for i in ensure_tuple(img): data = self._get_array_data(i) img_array.append(data) header = self._get_meta_dict(i) header[MetaKeys.ORIGINAL_AFFINE] = self._get_affine(i, self.affine_lps_to_ras) header[MetaKeys.SPACE] = SpaceKeys.RAS if self.affine_lps_to_ras else SpaceKeys.LPS header[MetaKeys.AFFINE] = header[MetaKeys.ORIGINAL_AFFINE].copy() header[MetaKeys.SPATIAL_SHAPE] = self._get_spatial_shape(i) if self.channel_dim is None: # default to "no_channel" or -1 header[MetaKeys.ORIGINAL_CHANNEL_DIM] = ( float("nan") if len(data.shape) == len(header[MetaKeys.SPATIAL_SHAPE]) else -1 ) else: header[MetaKeys.ORIGINAL_CHANNEL_DIM] = self.channel_dim _copy_compatible_dict(header, compatible_meta) return _stack_images(img_array, compatible_meta), compatible_meta
def _get_meta_dict(self, img) -> dict: """ Get all the metadata of the image and convert to dict type. Args: img: an ITK image object loaded from an image file. """ img_meta_dict = img.GetMetaDataDictionary() meta_dict = {} for key in img_meta_dict.GetKeys(): if key.startswith("ITK_"): continue val = img_meta_dict[key] meta_dict[key] = np.asarray(val) if type(val).__name__.startswith("itk") else val meta_dict["spacing"] = np.asarray(img.GetSpacing()) return meta_dict def _get_affine(self, img, lps_to_ras: bool = True): """ Get or construct the affine matrix of the image, it can be used to correct spacing, orientation or execute spatial transforms. Args: img: an ITK image object loaded from an image file. lps_to_ras: whether to convert the affine matrix from "LPS" to "RAS". Defaults to True. """ direction = itk.array_from_matrix(img.GetDirection()) spacing = np.asarray(img.GetSpacing()) origin = np.asarray(img.GetOrigin()) direction = np.asarray(direction) sr = min(max(direction.shape[0], 1), 3) affine: np.ndarray = np.eye(sr + 1) affine[:sr, :sr] = direction[:sr, :sr] @ np.diag(spacing[:sr]) affine[:sr, -1] = origin[:sr] if lps_to_ras: affine = orientation_ras_lps(affine) return affine def _get_spatial_shape(self, img): """ Get the spatial shape of `img`. Args: img: an ITK image object loaded from an image file. """ sr = itk.array_from_matrix(img.GetDirection()).shape[0] sr = max(min(sr, 3), 1) _size = list(itk.size(img)) if isinstance(self.channel_dim, int): _size.pop(self.channel_dim) return np.asarray(_size[:sr]) def _get_array_data(self, img): """ Get the raw array data of the image, converted to Numpy array. Following PyTorch conventions, the returned array data has contiguous channels, e.g. for an RGB image, all red channel image pixels are contiguous in memory. The last axis of the returned array is the channel axis. See also: - https://github.com/InsightSoftwareConsortium/ITK/blob/v5.2.1/Modules/Bridge/NumPy/wrapping/PyBuffer.i.in Args: img: an ITK image object loaded from an image file. """ np_img = itk.array_view_from_image(img, keep_axes=False) if img.GetNumberOfComponentsPerPixel() == 1: # handling spatial images return np_img if self.reverse_indexing else np_img.T # handling multi-channel images return np_img if self.reverse_indexing else np.moveaxis(np_img.T, 0, -1)
@require_pkg(pkg_name="pydicom") class PydicomReader(ImageReader): """ Load medical images based on Pydicom library. All the supported image formats can be found at: https://dicom.nema.org/medical/dicom/current/output/chtml/part10/chapter_7.html PydicomReader is also able to load segmentations, if a dicom file contains tag: `SegmentSequence`, the reader will consider it as segmentation data, and to load it successfully, `PerFrameFunctionalGroupsSequence` is required for dicom file, and for each frame of dicom file, `SegmentIdentificationSequence` is required. This method refers to the Highdicom library. This class refers to: https://nipy.org/nibabel/dicom/dicom_orientation.html#dicom-affine-formula https://github.com/pydicom/contrib-pydicom/blob/master/input-output/pydicom_series.py https://highdicom.readthedocs.io/en/latest/usage.html#parsing-segmentation-seg-images Args: channel_dim: the channel dimension of the input image, default is None. This is used to set original_channel_dim in the metadata, EnsureChannelFirstD reads this field. If None, `original_channel_dim` will be either `no_channel` or `-1`. affine_lps_to_ras: whether to convert the affine matrix from "LPS" to "RAS". Defaults to ``True``. Set to ``True`` to be consistent with ``NibabelReader``, otherwise the affine matrix remains in the Dicom convention. swap_ij: whether to swap the first two spatial axes. Default to ``True``, so that the outputs are consistent with the other readers. prune_metadata: whether to prune the saved information in metadata. This argument is used for `get_data` function. If True, only items that are related to the affine matrix will be saved. Default to ``True``. label_dict: label of the dicom data. If provided, it will be used when loading segmentation data. Keys of the dict are the classes, and values are the corresponding class number. For example: for TCIA collection "C4KC-KiTS", it can be: {"Kidney": 0, "Renal Tumor": 1}. kwargs: additional args for `pydicom.dcmread` API. more details about available args: https://pydicom.github.io/pydicom/stable/reference/generated/pydicom.filereader.dcmread.html#pydicom.filereader.dcmread If the `get_data` function will be called (for example, when using this reader with `monai.transforms.LoadImage`), please ensure that the argument `stop_before_pixels` is `True`, and `specific_tags` covers all necessary tags, such as `PixelSpacing`, `ImagePositionPatient`, `ImageOrientationPatient` and all `pixel_array` related tags. """ def __init__( self, channel_dim: str | int | None = None, affine_lps_to_ras: bool = True, swap_ij: bool = True, prune_metadata: bool = True, label_dict: dict | None = None, **kwargs, ): super().__init__() self.kwargs = kwargs self.channel_dim = float("nan") if channel_dim == "no_channel" else channel_dim self.affine_lps_to_ras = affine_lps_to_ras self.swap_ij = swap_ij self.prune_metadata = prune_metadata self.label_dict = label_dict def verify_suffix(self, filename: Sequence[PathLike] | PathLike) -> bool: """ Verify whether the specified file or files format is supported by Pydicom reader. Args: filename: file name or a list of file names to read. if a list of files, verify all the suffixes. """ return has_pydicom def read(self, data: Sequence[PathLike] | PathLike, **kwargs): """ Read image data from specified file or files, it can read a list of images and stack them together as multi-channel data in `get_data()`. If passing directory path instead of file path, will treat it as DICOM images series and read. Args: data: file name or a list of file names to read, kwargs: additional args for `pydicom.dcmread` API, will override `self.kwargs` for existing keys. Returns: If `data` represents a filename: return a pydicom dataset object. If `data` represents a list of filenames or a directory: return a list of pydicom dataset object. If `data` represents a list of directories: return a list of list of pydicom dataset object. """ img_ = [] filenames: Sequence[PathLike] = ensure_tuple(data) kwargs_ = self.kwargs.copy() kwargs_.update(kwargs) self.has_series = False for name in filenames: name = f"{name}" if Path(name).is_dir(): # read DICOM series series_slcs = glob.glob(os.path.join(name, "*")) series_slcs = [slc for slc in series_slcs if "LICENSE" not in slc] slices = [pydicom.dcmread(fp=slc, **kwargs_) for slc in series_slcs] img_.append(slices if len(slices) > 1 else slices[0]) if len(slices) > 1: self.has_series = True else: ds = pydicom.dcmread(fp=name, **kwargs_) img_.append(ds) return img_ if len(filenames) > 1 else img_[0] def _combine_dicom_series(self, data: Iterable): """ Combine dicom series (a list of pydicom dataset objects). Their data arrays will be stacked together at a new dimension as the last dimension. The stack order depends on Instance Number. The metadata will be based on the first slice's metadata, and some new items will be added: "spacing": the new spacing of the stacked slices. "lastImagePositionPatient": `ImagePositionPatient` for the last slice, it will be used to achieve the affine matrix. "spatial_shape": the spatial shape of the stacked slices. Args: data: a list of pydicom dataset objects. Returns: a tuple that consisted with data array and metadata. """ slices: list = [] # for a dicom series for slc_ds in data: if hasattr(slc_ds, "InstanceNumber"): slices.append(slc_ds) else: warnings.warn(f"slice: {slc_ds.filename} does not have InstanceNumber tag, skip it.") slices = sorted(slices, key=lambda s: s.InstanceNumber) if len(slices) == 0: raise ValueError("the input does not have valid slices.") first_slice = slices[0] average_distance = 0.0 first_array = self._get_array_data(first_slice) shape = first_array.shape spacing = getattr(first_slice, "PixelSpacing", [1.0, 1.0, 1.0]) prev_pos = getattr(first_slice, "ImagePositionPatient", (0.0, 0.0, 0.0))[2] stack_array = [first_array] for idx in range(1, len(slices)): slc_array = self._get_array_data(slices[idx]) slc_shape = slc_array.shape slc_spacing = getattr(slices[idx], "PixelSpacing", (1.0, 1.0, 1.0)) slc_pos = getattr(slices[idx], "ImagePositionPatient", (0.0, 0.0, float(idx)))[2] if not np.allclose(slc_spacing, spacing): warnings.warn(f"the list contains slices that have different spacings {spacing} and {slc_spacing}.") if shape != slc_shape: warnings.warn(f"the list contains slices that have different shapes {shape} and {slc_shape}.") average_distance += abs(prev_pos - slc_pos) prev_pos = slc_pos stack_array.append(slc_array) if len(slices) > 1: average_distance /= len(slices) - 1 spacing.append(average_distance) stack_array = np.stack(stack_array, axis=-1) stack_metadata = self._get_meta_dict(first_slice) stack_metadata["spacing"] = np.asarray(spacing) if hasattr(slices[-1], "ImagePositionPatient"): stack_metadata["lastImagePositionPatient"] = np.asarray(slices[-1].ImagePositionPatient) stack_metadata[MetaKeys.SPATIAL_SHAPE] = shape + (len(slices),) else: stack_array = stack_array[0] stack_metadata = self._get_meta_dict(first_slice) stack_metadata["spacing"] = np.asarray(spacing) stack_metadata[MetaKeys.SPATIAL_SHAPE] = shape return stack_array, stack_metadata def get_data(self, data) -> tuple[np.ndarray, dict]: """ Extract data array and metadata from loaded image and return them. This function returns two objects, first is numpy array of image data, second is dict of metadata. It constructs `affine`, `original_affine`, and `spatial_shape` and stores them in meta dict. For dicom series within the input, all slices will be stacked first, When loading a list of files (dicom file, or stacked dicom series), they are stacked together at a new dimension as the first dimension, and the metadata of the first image is used to represent the output metadata. To use this function, all pydicom dataset objects (if not segmentation data) should contain: `pixel_array`, `PixelSpacing`, `ImagePositionPatient` and `ImageOrientationPatient`. For segmentation data, we assume that the input is not a dicom series, and the object should contain `SegmentSequence` in order to identify it. In addition, tags (5200, 9229) and (5200, 9230) are required to achieve `PixelSpacing`, `ImageOrientationPatient` and `ImagePositionPatient`. Args: data: a pydicom dataset object, or a list of pydicom dataset objects, or a list of list of pydicom dataset objects. """ dicom_data = [] # combine dicom series if exists if self.has_series is True: # a list, all objects within a list belong to one dicom series if not isinstance(data[0], list): dicom_data.append(self._combine_dicom_series(data)) # a list of list, each inner list represents a dicom series else: for series in data: dicom_data.append(self._combine_dicom_series(series)) else: # a single pydicom dataset object if not isinstance(data, list): data = [data] for d in data: if hasattr(d, "SegmentSequence"): data_array, metadata = self._get_seg_data(d) else: data_array = self._get_array_data(d) metadata = self._get_meta_dict(d) metadata[MetaKeys.SPATIAL_SHAPE] = data_array.shape dicom_data.append((data_array, metadata)) img_array: list[np.ndarray] = [] compatible_meta: dict = {} for data_array, metadata in ensure_tuple(dicom_data): img_array.append(np.ascontiguousarray(np.swapaxes(data_array, 0, 1) if self.swap_ij else data_array)) affine = self._get_affine(metadata, self.affine_lps_to_ras) metadata[MetaKeys.SPACE] = SpaceKeys.RAS if self.affine_lps_to_ras else SpaceKeys.LPS if self.swap_ij: affine = affine @ np.array([[0, 1, 0, 0], [1, 0, 0, 0], [0, 0, 1, 0], [0, 0, 0, 1]]) sp_size = list(metadata[MetaKeys.SPATIAL_SHAPE]) sp_size[0], sp_size[1] = sp_size[1], sp_size[0] metadata[MetaKeys.SPATIAL_SHAPE] = ensure_tuple(sp_size) metadata[MetaKeys.ORIGINAL_AFFINE] = affine metadata[MetaKeys.AFFINE] = affine.copy() if self.channel_dim is None: # default to "no_channel" or -1 metadata[MetaKeys.ORIGINAL_CHANNEL_DIM] = ( float("nan") if len(data_array.shape) == len(metadata[MetaKeys.SPATIAL_SHAPE]) else -1 ) else: metadata[MetaKeys.ORIGINAL_CHANNEL_DIM] = self.channel_dim metadata["spacing"] = affine_to_spacing( metadata[MetaKeys.ORIGINAL_AFFINE], r=len(metadata[MetaKeys.SPATIAL_SHAPE]) ) _copy_compatible_dict(metadata, compatible_meta) return _stack_images(img_array, compatible_meta), compatible_meta def _get_meta_dict(self, img) -> dict: """ Get all the metadata of the image and convert to dict type. Args: img: a Pydicom dataset object. """ metadata = img.to_json_dict(suppress_invalid_tags=True) if self.prune_metadata: prune_metadata = {} for key in ["00200037", "00200032", "00280030", "52009229", "52009230"]: if key in metadata.keys(): prune_metadata[key] = metadata[key] return prune_metadata # always remove Pixel Data "7FE00008" or "7FE00009" or "7FE00010" # always remove Data Set Trailing Padding "FFFCFFFC" for key in ["7FE00008", "7FE00009", "7FE00010", "FFFCFFFC"]: if key in metadata.keys(): metadata.pop(key) return metadata # type: ignore def _get_affine(self, metadata: dict, lps_to_ras: bool = True): """ Get or construct the affine matrix of the image, it can be used to correct spacing, orientation or execute spatial transforms. Args: metadata: metadata with dict type. lps_to_ras: whether to convert the affine matrix from "LPS" to "RAS". Defaults to True. """ affine: np.ndarray = np.eye(4) if not ("00200037" in metadata and "00200032" in metadata): return affine # "00200037" is the tag of `ImageOrientationPatient` rx, ry, rz, cx, cy, cz = metadata["00200037"]["Value"] # "00200032" is the tag of `ImagePositionPatient` sx, sy, sz = metadata["00200032"]["Value"] # "00280030" is the tag of `PixelSpacing` spacing = metadata["00280030"]["Value"] if "00280030" in metadata else (1.0, 1.0) dr, dc = metadata.get("spacing", spacing)[:2] affine[0, 0] = cx * dr affine[0, 1] = rx * dc affine[0, 3] = sx affine[1, 0] = cy * dr affine[1, 1] = ry * dc affine[1, 3] = sy affine[2, 0] = cz * dr affine[2, 1] = rz * dc affine[2, 2] = 1.0 affine[2, 3] = sz # 3d if "lastImagePositionPatient" in metadata: t1n, t2n, t3n = metadata["lastImagePositionPatient"] n = metadata[MetaKeys.SPATIAL_SHAPE][-1] k1, k2, k3 = (t1n - sx) / (n - 1), (t2n - sy) / (n - 1), (t3n - sz) / (n - 1) affine[0, 2] = k1 affine[1, 2] = k2 affine[2, 2] = k3 if lps_to_ras: affine = orientation_ras_lps(affine) return affine def _get_frame_data(self, img) -> Iterator: """ yield frames and description from the segmentation image. This function is adapted from Highdicom: https://github.com/herrmannlab/highdicom/blob/v0.18.2/src/highdicom/seg/utils.py which has the following license... # ========================================================================= # https://github.com/herrmannlab/highdicom/blob/v0.18.2/LICENSE # # Copyright 2020 MGH Computational Pathology # Permission is hereby granted, free of charge, to any person obtaining a # copy of this software and associated documentation files (the # "Software"), to deal in the Software without restriction, including # without limitation the rights to use, copy, modify, merge, publish, # distribute, sublicense, and/or sell copies of the Software, and to # permit persons to whom the Software is furnished to do so, subject to # the following conditions: # The above copyright notice and this permission notice shall be included # in all copies or substantial portions of the Software. # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS # OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF # MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. # IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY # CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, # TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE # SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. # ========================================================================= (https://github.com/herrmannlab/highdicom/issues/188) Args: img: a Pydicom dataset object that has attribute "SegmentSequence". """ if not hasattr(img, "PerFrameFunctionalGroupsSequence"): raise NotImplementedError( f"To read dicom seg: {img.filename}, 'PerFrameFunctionalGroupsSequence' is required." ) frame_seg_nums = [] for f in img.PerFrameFunctionalGroupsSequence: if not hasattr(f, "SegmentIdentificationSequence"): raise NotImplementedError( f"To read dicom seg: {img.filename}, 'SegmentIdentificationSequence' is required for each frame." ) frame_seg_nums.append(int(f.SegmentIdentificationSequence[0].ReferencedSegmentNumber)) frame_seg_nums_arr = np.array(frame_seg_nums) seg_descriptions = {int(f.SegmentNumber): f for f in img.SegmentSequence} for i in np.unique(frame_seg_nums_arr): indices = np.where(frame_seg_nums_arr == i)[0] yield (img.pixel_array[indices, ...], seg_descriptions[i]) def _get_seg_data(self, img): """ Get the array data and metadata of the segmentation image. Aegs: img: a Pydicom dataset object that has attribute "SegmentSequence". """ metadata = self._get_meta_dict(img) n_classes = len(img.SegmentSequence) spatial_shape = list(img.pixel_array.shape) spatial_shape[0] = spatial_shape[0] // n_classes if self.label_dict is not None: metadata["labels"] = self.label_dict all_segs = np.zeros([*spatial_shape, len(self.label_dict)]) else: metadata["labels"] = {} all_segs = np.zeros([*spatial_shape, n_classes]) for i, (frames, description) in enumerate(self._get_frame_data(img)): segment_label = getattr(description, "SegmentLabel", f"label_{i}") class_name = getattr(description, "SegmentDescription", segment_label) if class_name not in metadata["labels"].keys(): metadata["labels"][class_name] = i class_num = metadata["labels"][class_name] all_segs[..., class_num] = frames all_segs = all_segs.transpose([1, 2, 0, 3]) metadata[MetaKeys.SPATIAL_SHAPE] = all_segs.shape[:-1] if "52009229" in metadata.keys(): shared_func_group_seq = metadata["52009229"]["Value"][0] # get `ImageOrientationPatient` if "00209116" in shared_func_group_seq.keys(): plane_orient_seq = shared_func_group_seq["00209116"]["Value"][0] if "00200037" in plane_orient_seq.keys(): metadata["00200037"] = plane_orient_seq["00200037"] # get `PixelSpacing` if "00289110" in shared_func_group_seq.keys(): pixel_measure_seq = shared_func_group_seq["00289110"]["Value"][0] if "00280030" in pixel_measure_seq.keys(): pixel_spacing = pixel_measure_seq["00280030"]["Value"] metadata["spacing"] = pixel_spacing if "00180050" in pixel_measure_seq.keys(): metadata["spacing"] += pixel_measure_seq["00180050"]["Value"] if self.prune_metadata: metadata.pop("52009229") # get `ImagePositionPatient` if "52009230" in metadata.keys(): first_frame_func_group_seq = metadata["52009230"]["Value"][0] if "00209113" in first_frame_func_group_seq.keys(): plane_position_seq = first_frame_func_group_seq["00209113"]["Value"][0] if "00200032" in plane_position_seq.keys(): metadata["00200032"] = plane_position_seq["00200032"] metadata["lastImagePositionPatient"] = metadata["52009230"]["Value"][-1]["00209113"]["Value"][0][ "00200032" ]["Value"] if self.prune_metadata: metadata.pop("52009230") return all_segs, metadata def _get_array_data(self, img): """ Get the array data of the image. If `RescaleSlope` and `RescaleIntercept` are available, the raw array data will be rescaled. The output data has the dtype np.float32 if the rescaling is applied. Args: img: a Pydicom dataset object. """ # process Dicom series if not hasattr(img, "pixel_array"): raise ValueError(f"dicom data: {img.filename} does not have pixel_array.") data = img.pixel_array slope, offset = 1.0, 0.0 rescale_flag = False if hasattr(img, "RescaleSlope"): slope = img.RescaleSlope rescale_flag = True if hasattr(img, "RescaleIntercept"): offset = img.RescaleIntercept rescale_flag = True if rescale_flag: data = data.astype(np.float32) * slope + offset return data
[docs] @require_pkg(pkg_name="nibabel") class NibabelReader(ImageReader): """ Load NIfTI format images based on Nibabel library. Args: as_closest_canonical: if True, load the image as closest to canonical axis format. squeeze_non_spatial_dims: if True, non-spatial singletons will be squeezed, e.g. (256,256,1,3) -> (256,256,3) channel_dim: the channel dimension of the input image, default is None. this is used to set original_channel_dim in the metadata, EnsureChannelFirstD reads this field. if None, `original_channel_dim` will be either `no_channel` or `-1`. most Nifti files are usually "channel last", no need to specify this argument for them. kwargs: additional args for `nibabel.load` API. more details about available args: https://github.com/nipy/nibabel/blob/master/nibabel/loadsave.py """ def __init__( self, channel_dim: str | int | None = None, as_closest_canonical: bool = False, squeeze_non_spatial_dims: bool = False, **kwargs, ): super().__init__() self.channel_dim = float("nan") if channel_dim == "no_channel" else channel_dim self.as_closest_canonical = as_closest_canonical self.squeeze_non_spatial_dims = squeeze_non_spatial_dims self.kwargs = kwargs
[docs] def verify_suffix(self, filename: Sequence[PathLike] | PathLike) -> bool: """ Verify whether the specified file or files format is supported by Nibabel reader. Args: filename: file name or a list of file names to read. if a list of files, verify all the suffixes. """ suffixes: Sequence[str] = ["nii", "nii.gz"] return has_nib and is_supported_format(filename, suffixes)
[docs] def read(self, data: Sequence[PathLike] | PathLike, **kwargs): """ Read image data from specified file or files, it can read a list of images and stack them together as multi-channel data in `get_data()`. Note that the returned object is Nibabel image object or list of Nibabel image objects. Args: data: file name or a list of file names to read. kwargs: additional args for `nibabel.load` API, will override `self.kwargs` for existing keys. More details about available args: https://github.com/nipy/nibabel/blob/master/nibabel/loadsave.py """ img_: list[Nifti1Image] = [] filenames: Sequence[PathLike] = ensure_tuple(data) kwargs_ = self.kwargs.copy() kwargs_.update(kwargs) for name in filenames: img = nib.load(name, **kwargs_) img = correct_nifti_header_if_necessary(img) img_.append(img) # type: ignore return img_ if len(filenames) > 1 else img_[0]
[docs] def get_data(self, img) -> tuple[np.ndarray, dict]: """ Extract data array and metadata from loaded image and return them. This function returns two objects, first is numpy array of image data, second is dict of metadata. It constructs `affine`, `original_affine`, and `spatial_shape` and stores them in meta dict. When loading a list of files, they are stacked together at a new dimension as the first dimension, and the metadata of the first image is used to present the output metadata. Args: img: a Nibabel image object loaded from an image file or a list of Nibabel image objects. """ img_array: list[np.ndarray] = [] compatible_meta: dict = {} for i in ensure_tuple(img): header = self._get_meta_dict(i) header[MetaKeys.AFFINE] = self._get_affine(i) header[MetaKeys.ORIGINAL_AFFINE] = self._get_affine(i) header["as_closest_canonical"] = self.as_closest_canonical if self.as_closest_canonical: i = nib.as_closest_canonical(i) header[MetaKeys.AFFINE] = self._get_affine(i) header[MetaKeys.SPATIAL_SHAPE] = self._get_spatial_shape(i) header[MetaKeys.SPACE] = SpaceKeys.RAS data = self._get_array_data(i) if self.squeeze_non_spatial_dims: for d in range(len(data.shape), len(header[MetaKeys.SPATIAL_SHAPE]), -1): if data.shape[d - 1] == 1: data = data.squeeze(axis=d - 1) img_array.append(data) if self.channel_dim is None: # default to "no_channel" or -1 header[MetaKeys.ORIGINAL_CHANNEL_DIM] = ( float("nan") if len(data.shape) == len(header[MetaKeys.SPATIAL_SHAPE]) else -1 ) else: header[MetaKeys.ORIGINAL_CHANNEL_DIM] = self.channel_dim _copy_compatible_dict(header, compatible_meta) return _stack_images(img_array, compatible_meta), compatible_meta
def _get_meta_dict(self, img) -> dict: """ Get the all the metadata of the image and convert to dict type. Args: img: a Nibabel image object loaded from an image file. """ # swap to little endian as PyTorch doesn't support big endian try: header = img.header.as_byteswapped("<") except ValueError: header = img.header return dict(header) def _get_affine(self, img): """ Get the affine matrix of the image, it can be used to correct spacing, orientation or execute spatial transforms. Args: img: a Nibabel image object loaded from an image file. """ return np.array(img.affine, copy=True) def _get_spatial_shape(self, img): """ Get the spatial shape of image data, it doesn't contain the channel dim. Args: img: a Nibabel image object loaded from an image file. """ # swap to little endian as PyTorch doesn't support big endian try: header = img.header.as_byteswapped("<") except ValueError: header = img.header dim = header.get("dim", None) if dim is None: dim = header.get("dims") # mgh format? dim = np.insert(dim, 0, 3) ndim = dim[0] size = list(dim[1:]) if not is_no_channel(self.channel_dim): size.pop(int(self.channel_dim)) # type: ignore spatial_rank = max(min(ndim, 3), 1) return np.asarray(size[:spatial_rank]) def _get_array_data(self, img): """ Get the raw array data of the image, converted to Numpy array. Args: img: a Nibabel image object loaded from an image file. """ return np.asanyarray(img.dataobj, order="C")
[docs] class NumpyReader(ImageReader): """ Load NPY or NPZ format data based on Numpy library, they can be arrays or pickled objects. A typical usage is to load the `mask` data for classification task. It can load part of the npz file with specified `npz_keys`. Args: npz_keys: if loading npz file, only load the specified keys, if None, load all the items. stack the loaded items together to construct a new first dimension. channel_dim: if not None, explicitly specify the channel dim, otherwise, treat the array as no channel. kwargs: additional args for `numpy.load` API except `allow_pickle`. more details about available args: https://numpy.org/doc/stable/reference/generated/numpy.load.html """ def __init__(self, npz_keys: KeysCollection | None = None, channel_dim: str | int | None = None, **kwargs): super().__init__() if npz_keys is not None: npz_keys = ensure_tuple(npz_keys) self.npz_keys = npz_keys self.channel_dim = float("nan") if channel_dim == "no_channel" else channel_dim self.kwargs = kwargs
[docs] def verify_suffix(self, filename: Sequence[PathLike] | PathLike) -> bool: """ Verify whether the specified file or files format is supported by Numpy reader. Args: filename: file name or a list of file names to read. if a list of files, verify all the suffixes. """ suffixes: Sequence[str] = ["npz", "npy"] return is_supported_format(filename, suffixes)
[docs] def read(self, data: Sequence[PathLike] | PathLike, **kwargs): """ Read image data from specified file or files, it can read a list of data files and stack them together as multi-channel data in `get_data()`. Note that the returned object is Numpy array or list of Numpy arrays. Args: data: file name or a list of file names to read. kwargs: additional args for `numpy.load` API except `allow_pickle`, will override `self.kwargs` for existing keys. More details about available args: https://numpy.org/doc/stable/reference/generated/numpy.load.html """ img_: list[Nifti1Image] = [] filenames: Sequence[PathLike] = ensure_tuple(data) kwargs_ = self.kwargs.copy() kwargs_.update(kwargs) for name in filenames: img = np.load(name, allow_pickle=True, **kwargs_) if Path(name).name.endswith(".npz"): # load expected items from NPZ file npz_keys = [f"arr_{i}" for i in range(len(img))] if self.npz_keys is None else self.npz_keys for k in npz_keys: img_.append(img[k]) else: img_.append(img) return img_ if len(img_) > 1 else img_[0]
[docs] def get_data(self, img) -> tuple[np.ndarray, dict]: """ Extract data array and metadata from loaded image and return them. This function returns two objects, first is numpy array of image data, second is dict of metadata. It constructs `affine`, `original_affine`, and `spatial_shape` and stores them in meta dict. When loading a list of files, they are stacked together at a new dimension as the first dimension, and the metadata of the first image is used to represent the output metadata. Args: img: a Numpy array loaded from a file or a list of Numpy arrays. """ img_array: list[np.ndarray] = [] compatible_meta: dict = {} if isinstance(img, np.ndarray): img = (img,) for i in ensure_tuple(img): header: dict[MetaKeys, Any] = {} if isinstance(i, np.ndarray): # if `channel_dim` is None, can not detect the channel dim, use all the dims as spatial_shape spatial_shape = np.asarray(i.shape) if isinstance(self.channel_dim, int): spatial_shape = np.delete(spatial_shape, self.channel_dim) header[MetaKeys.SPATIAL_SHAPE] = spatial_shape header[MetaKeys.SPACE] = SpaceKeys.RAS img_array.append(i) header[MetaKeys.ORIGINAL_CHANNEL_DIM] = ( self.channel_dim if isinstance(self.channel_dim, int) else float("nan") ) _copy_compatible_dict(header, compatible_meta) return _stack_images(img_array, compatible_meta), compatible_meta
[docs] @require_pkg(pkg_name="PIL") class PILReader(ImageReader): """ Load common 2D image format (supports PNG, JPG, BMP) file or files from provided path. Args: converter: additional function to convert the image data after `read()`. for example, use `converter=lambda image: image.convert("LA")` to convert image format. reverse_indexing: whether to swap axis 0 and 1 after loading the array, this is enabled by default, so that output of the reader is consistent with the other readers. Set this option to ``False`` to use the PIL backend's original spatial axes convention. kwargs: additional args for `Image.open` API in `read()`, mode details about available args: https://pillow.readthedocs.io/en/stable/reference/Image.html#PIL.Image.open """ def __init__(self, converter: Callable | None = None, reverse_indexing: bool = True, **kwargs): super().__init__() self.converter = converter self.reverse_indexing = reverse_indexing self.kwargs = kwargs
[docs] def verify_suffix(self, filename: Sequence[PathLike] | PathLike) -> bool: """ Verify whether the specified file or files format is supported by PIL reader. Args: filename: file name or a list of file names to read. if a list of files, verify all the suffixes. """ suffixes: Sequence[str] = ["png", "jpg", "jpeg", "bmp"] return has_pil and is_supported_format(filename, suffixes)
[docs] def read(self, data: Sequence[PathLike] | PathLike | np.ndarray, **kwargs): """ Read image data from specified file or files, it can read a list of images and stack them together as multi-channel data in `get_data()`. Note that the returned object is PIL image or list of PIL image. Args: data: file name or a list of file names to read. kwargs: additional args for `Image.open` API in `read()`, will override `self.kwargs` for existing keys. Mode details about available args: https://pillow.readthedocs.io/en/stable/reference/Image.html#PIL.Image.open """ img_: list[PILImage.Image] = [] filenames: Sequence[PathLike] = ensure_tuple(data) kwargs_ = self.kwargs.copy() kwargs_.update(kwargs) for name in filenames: img = PILImage.open(name, **kwargs_) if callable(self.converter): img = self.converter(img) img_.append(img) return img_ if len(filenames) > 1 else img_[0]
[docs] def get_data(self, img) -> tuple[np.ndarray, dict]: """ Extract data array and metadata from loaded image and return them. This function returns two objects, first is numpy array of image data, second is dict of metadata. It computes `spatial_shape` and stores it in meta dict. When loading a list of files, they are stacked together at a new dimension as the first dimension, and the metadata of the first image is used to represent the output metadata. Note that by default `self.reverse_indexing` is set to ``True``, which swaps axis 0 and 1 after loading the array because the spatial axes definition in PIL is different from other common medical packages. Args: img: a PIL Image object loaded from a file or a list of PIL Image objects. """ img_array: list[np.ndarray] = [] compatible_meta: dict = {} for i in ensure_tuple(img): header = self._get_meta_dict(i) header[MetaKeys.SPATIAL_SHAPE] = self._get_spatial_shape(i) data = np.moveaxis(np.asarray(i), 0, 1) if self.reverse_indexing else np.asarray(i) img_array.append(data) header[MetaKeys.ORIGINAL_CHANNEL_DIM] = ( float("nan") if len(data.shape) == len(header[MetaKeys.SPATIAL_SHAPE]) else -1 ) _copy_compatible_dict(header, compatible_meta) return _stack_images(img_array, compatible_meta), compatible_meta
def _get_meta_dict(self, img) -> dict: """ Get the all the metadata of the image and convert to dict type. Args: img: a PIL Image object loaded from an image file. """ return {"format": img.format, "mode": img.mode, "width": img.width, "height": img.height} def _get_spatial_shape(self, img): """ Get the spatial shape of image data, it doesn't contain the channel dim. Args: img: a PIL Image object loaded from an image file. """ return np.asarray((img.width, img.height))
@dataclass class NrrdImage: """Class to wrap nrrd image array and metadata header""" array: np.ndarray header: dict
[docs] @require_pkg(pkg_name="nrrd") class NrrdReader(ImageReader): """ Load NRRD format images based on pynrrd library. Args: channel_dim: the channel dimension of the input image, default is None. This is used to set original_channel_dim in the metadata, EnsureChannelFirstD reads this field. If None, `original_channel_dim` will be either `no_channel` or `0`. NRRD files are usually "channel first". dtype: dtype of the data array when loading image. index_order: Specify whether the returned data array should be in C-order (‘C’) or Fortran-order (‘F’). Numpy is usually in C-order, but default on the NRRD header is F affine_lps_to_ras: whether to convert the affine matrix from "LPS" to "RAS". Defaults to ``True``. Set to ``True`` to be consistent with ``NibabelReader``, otherwise the affine matrix is unmodified. kwargs: additional args for `nrrd.read` API. more details about available args: https://github.com/mhe/pynrrd/blob/master/nrrd/reader.py """ def __init__( self, channel_dim: str | int | None = None, dtype: np.dtype | type | str | None = np.float32, index_order: str = "F", affine_lps_to_ras: bool = True, **kwargs, ): self.channel_dim = float("nan") if channel_dim == "no_channel" else channel_dim self.dtype = dtype self.index_order = index_order self.affine_lps_to_ras = affine_lps_to_ras self.kwargs = kwargs
[docs] def verify_suffix(self, filename: Sequence[PathLike] | PathLike) -> bool: """ Verify whether the specified `filename` is supported by pynrrd reader. Args: filename: file name or a list of file names to read. if a list of files, verify all the suffixes. """ suffixes: Sequence[str] = ["nrrd", "seg.nrrd"] return has_nrrd and is_supported_format(filename, suffixes)
[docs] def read(self, data: Sequence[PathLike] | PathLike, **kwargs) -> Sequence[Any] | Any: """ Read image data from specified file or files. Note that it returns a data object or a sequence of data objects. Args: data: file name or a list of file names to read. kwargs: additional args for actual `read` API of 3rd party libs. """ img_: list = [] filenames: Sequence[PathLike] = ensure_tuple(data) kwargs_ = self.kwargs.copy() kwargs_.update(kwargs) for name in filenames: nrrd_image = NrrdImage(*nrrd.read(name, index_order=self.index_order, *kwargs_)) img_.append(nrrd_image) return img_ if len(filenames) > 1 else img_[0]
[docs] def get_data(self, img: NrrdImage | list[NrrdImage]) -> tuple[np.ndarray, dict]: """ Extract data array and metadata from loaded image and return them. This function must return two objects, the first is a numpy array of image data, the second is a dictionary of metadata. Args: img: a `NrrdImage` loaded from an image file or a list of image objects. """ img_array: list[np.ndarray] = [] compatible_meta: dict = {} for i in ensure_tuple(img): data = i.array.astype(self.dtype) img_array.append(data) header = dict(i.header) if self.index_order == "C": header = self._convert_f_to_c_order(header) header[MetaKeys.ORIGINAL_AFFINE] = self._get_affine(i) if self.affine_lps_to_ras: header = self._switch_lps_ras(header) if header.get(MetaKeys.SPACE, "left-posterior-superior") == "left-posterior-superior": header[MetaKeys.SPACE] = SpaceKeys.LPS # assuming LPS if not specified header[MetaKeys.AFFINE] = header[MetaKeys.ORIGINAL_AFFINE].copy() header[MetaKeys.SPATIAL_SHAPE] = header["sizes"] [header.pop(k) for k in ("sizes", "space origin", "space directions")] # rm duplicated data in header if self.channel_dim is None: # default to "no_channel" or -1 header[MetaKeys.ORIGINAL_CHANNEL_DIM] = ( float("nan") if len(data.shape) == len(header[MetaKeys.SPATIAL_SHAPE]) else 0 ) else: header[MetaKeys.ORIGINAL_CHANNEL_DIM] = self.channel_dim _copy_compatible_dict(header, compatible_meta) return _stack_images(img_array, compatible_meta), compatible_meta
def _get_affine(self, img: NrrdImage) -> np.ndarray: """ Get the affine matrix of the image, it can be used to correct spacing, orientation or execute spatial transforms. Args: img: A `NrrdImage` loaded from image file """ direction = img.header["space directions"] origin = img.header["space origin"] x, y = direction.shape affine_diam = min(x, y) + 1 affine: np.ndarray = np.eye(affine_diam) affine[:x, :y] = direction affine[: (affine_diam - 1), -1] = origin # len origin is always affine_diam - 1 return affine def _switch_lps_ras(self, header: dict) -> dict: """ For compatibility with nibabel, switch from LPS to RAS. Adapt affine matrix and `space` argument in header accordingly. If no information of space is given in the header, LPS is assumed and thus converted to RAS. If information about space is given, but is not LPS, the unchanged header is returned. Args: header: The image metadata as dict """ if "space" not in header or header["space"] == "left-posterior-superior": header[MetaKeys.ORIGINAL_AFFINE] = orientation_ras_lps(header[MetaKeys.ORIGINAL_AFFINE]) header[MetaKeys.SPACE] = SpaceKeys.RAS return header def _convert_f_to_c_order(self, header: dict) -> dict: """ All header fields of a NRRD are specified in `F` (Fortran) order, even if the image was read as C-ordered array. 1D arrays of header['space origin'] and header['sizes'] become inverted, e.g, [1,2,3] -> [3,2,1] The 2D Array for header['space directions'] is transposed: [[1,0,0],[0,2,0],[0,0,3]] -> [[3,0,0],[0,2,0],[0,0,1]] For more details refer to: https://pynrrd.readthedocs.io/en/latest/user-guide.html#index-ordering Args: header: The image metadata as dict """ header["space directions"] = np.rot90(np.flip(header["space directions"], 0)) header["space origin"] = header["space origin"][::-1] header["sizes"] = header["sizes"][::-1] return header